Longevity Tied to Genes That Preserve Tips of Chromosomes

Longevity Tied to Genes That Preserve Tips of Chromosomes

ScienceDaily (Nov. 15, 2009) — A team led by researchers at Albert Einstein College of Medicine of Yeshiva University has found a clear link between living to 100 and inheriting a hyperactive version of an enzyme that rebuilds telomeres -- the tip ends of chromosomes.

The findings appear in a recent issue of the Proceedings of the National Academy of Sciences.

Telomeres play crucial roles in aging, cancer and other biological processes. Their importance was recognized last month, when three scientists were awarded the 2009 Nobel Prize in Physiology and Medicine for determining the structure of telomeres and discovering how they protect chromosomes from degrading.

Telomeres are relatively short sections of specialized DNA that sit at the ends of all chromosomes. One of the Nobel Prize winners, Elizabeth Blackburn, Ph.D., of the University of California at San Francisco, has compared telomeres to the plastic tips at the ends of shoelaces that prevent the laces from unraveling.

Each time a cell divides, its telomeres erode slightly and become progressively shorter with each cell division. Eventually, telomeres become so short that their host cells stop dividing and lapse into a condition called cell senescence. As a result, vital tissues and important organs begin to fail and the classical signs of aging ensue.

In investigating the role of telomeres in aging, the Einstein researchers studied Ashkenazi Jews because they are a homogeneous population that was already well studied genetically. Three groups were enrolled: 86 very old -- but generally healthy -- Gil Atzmon, Ph.D.people (average age 97); 175 of their offspring; and 93 controls (offspring of parents who had lived a normal lifespan).

"Telomeres are one piece of the puzzle that accounts for why some people can live so long," says Gil Atzmon, Ph.D., assistant professor of medicine and of genetics at Einstein, Genetic Core Leader for The LonGenity Project at Einstein's Institute for Aging Research, and a lead author of the paper. "Our research was meant to answer two questions: Do people who live long lives tend to have long telomeres? And if so, could variations in their genes that code for telomerase account for their long telomeres?"

The answer to both questions was "yes."

Bubbling Ball of Gas: SUNRISE Telescope Delivers Spectacular Pictures of Sun's Surface

The IMaX instrument not only depicts the solar surface, it also makes magnetic fields visible; these appear as black or white structures in the polarised light. SUNRISE enables tiny magnetic fields on the surface of the Sun to be measured at a level of detail never before achieved. (Credit: Image: MPS/IMAX consortium)







Bubbling Ball of Gas: SUNRISE Telescope Delivers Spectacular Pictures of Sun's Surface

ScienceDaily (Nov. 14, 2009) — The Sun is a bubbling mass. Packages of gas rise and sink, lending the sun its grainy surface structure, its granulation. Dark spots appear and disappear, clouds of matter dart up -- and behind the whole thing are the magnetic fields, the engines of it all. The SUNRISE balloon-borne telescope, a collaborative project between the Max Planck Institute for Solar System Research in Katlenburg-Lindau and partners in Germany, Spain and the USA, has now delivered images that show the complex interplay on the solar surface to a level of detail never before achieved.

The largest solar telescope ever to have left Earth was launched from the ESRANGE Space Centre in Kiruna, northern Sweden, on June 8, 2009. The total equipment weighed in at more than six tons on launch. Carried by a gigantic helium balloon with a capacity of a million cubic metres and a diameter of around 130 metres, SUNRISE reached a cruising altitude of 37 kilometres above the Earth's surface.

The observation conditions in this layer of the atmosphere, known as the stratosphere, are similar to those in outer space: for one thing, the images are no longer affected by air turbulence; and for another, the camera can also zoom in on the Sun in ultraviolet light, which would otherwise be absorbed by the ozone layer. After separating from the balloon, SUNRISE parachuted safely down to Earth on June 14th, landing on Somerset Island, a large island in Canada's Nunavut Territory situated in the Northwest Passage, the seaway through the Arctic Ocean between the Atlantic and the Pacific.

NASA to try to free stuck Mars rover Spirit

This image provided by NASA shows the surface of Mars as seen from the stuck Mars rover, Spirit. The rover will soon try to drive itself out of a sand trap where it has been stuck for the past six months. NASA is set to outline plans to try to free Spirit, a risky process that could take months.
(AP Photo/NASA)


NASA to try to free stuck Mars rover Spirit

LOS ANGELES – For NASA's stuck Mars rover, the Spirit may be willing, but the wheels could prove too weak. The space agency on Thursday outlined a rescue plan to try to free the rover Spirit, which has been bogged in a sand trap on the red planet for half a year. The risky operation is expected to last several months.

"If it cannot make the great escape from this sand trap, it's likely that this lonely spot straddling the edge of this crater might be where Spirit ends its adventures on Mars," said Doug McCuistion, who heads the Mars exploration program at NASA headquarters.

The plucky rover was driving backward in April when its wheels broke through the crusty surface and became mired in a patch of talcum-like dirt. It tried to crab its way out, but its wheels sunk deeper.

After rehearsing various escape tries on Earth using prototype rovers, NASA said it was finally ready to provide some roadside assistance on Mars.

The first driving commands will be sent to Spirit on Monday, but engineers cautioned the wheels likely will have high slippage.

The plans calls for Spirit to drive forward and retrace its steps.

"If we follow our old tracks out, we may be able to make better progress," said rover driver Ashley Stroupe of NASA's Jet Propulsion Laboratory.

Did a Time-Traveling Bird Sabotage the Collider?

Did a Time-Traveling Bird Sabotage the Collider?

Sometime on Nov. 3, the supercooled magnets in sector 81 of the Large Hadron Collider (LHC), outside Geneva, began to dangerously overheat. Scientists rushed to diagnose the problem, since the particle accelerator has to maintain a temperature colder than deep space in order to work. The culprit? "A bit of baguette," says Mike Lamont of the control center of CERN, the European Organization for Nuclear Research, which built and maintains the LHC. Apparently, a passing bird may have dropped the chunk of bread on an electrical substation above the accelerator, causing a power cut. The baguette was removed, power to the cryogenic system was restored and within a few days the magnets returned to their supercool temperatures.

While most scientists would write off the event as a freak accident, two esteemed physicists have formulated a theory that suggests an alternative explanation: perhaps a time-traveling bird was sent from the future to sabotage the experiment. Bech Nielsen of the Niels Bohr Institute in Copenhagen and Masao Ninomiya of the Yukawa Institute for Theoretical Physics in Kyoto, Japan, have published several papers over the past year arguing that the CERN experiment may be the latest in a series of physics research projects whose purposes are so unacceptable to the universe that they are doomed to fail, subverted by the future. (See pictures of the Large Hadron Particle Collider.)

The LHC, a 17-mile underground ring designed to smash atoms together at high energies, was created in part to find proof of a hypothetical subatomic particle called the Higgs boson. According to current theory, the Higgs is responsible for imparting mass to all things in the universe. But ever since the British physicist Peter Higgs first postulated the existence of the particle in 1964, attempts to capture the particle have failed, and often for unexpected, seemingly inexplicable reasons.

In 1993, the multibillion-dollar United States Superconducting Supercollider, which was designed to search for the Higgs, was abruptly canceled by Congress. In 2000, scientists at a previous CERN accelerator, LEP, said they were on the verge of discovering the particle when, again, funding dried up. And now there's the LHC. Originally scheduled to start operating in 2006, it has been hit with a series of delays and setbacks, including a sudden explosion between two magnets nine days after the accelerator was first turned on, the arrest of one of its contributing physicists on suspicion of terrorist activity and, most recently, the aerial bread bombardment from a bird. (A CERN spokesman said power cuts such as the one caused by the errant baguette are common for a device that requires as much electricity as the nearby city of Geneva, and that physicists are confident they will begin circulating atoms by the end of the year).

Read more: http://www.time.com/time/health/article/0,8599,1937370,00.html#ixzz0WrZ3HdV2

Two Earth-sized Bodies With Oxygen Rich Atmospheres Found, But They're Stars

Two Earth-sized Bodies With Oxygen Rich Atmospheres Found, But They're Stars Not Planets

ScienceDaily (Nov. 13, 2009) — Astrophysicists at the University of Warwick and Kiel University have discovered two earth sized bodies with oxygen rich atmospheres -- however there is a bit of a disappointing snag for anyone looking for a potential home for alien life, or even a future home for ourselves, as they are not planets but are actually two unusual white dwarf stars.

The two white dwarf stars SDSS 0922+2928 and SDSS 1102+2054 are 400 and 220 light years from Earth. They are both the remnants of massive stars that are at the end of their stellar evolution having consumed all the material they had available for nuclear fusion.

Theoretical models suggest that massive stars (around 7 -- 10 times the mass of our own Sun) will consume all of their hydrogen, helium and carbon, and end their lives either as white dwarfs with very oxygen-rich cores, or undergo a supernova and collapse into neutron stars. Finding such oxygen-rich white dwarfs would be an important confirmation of the models.

Unfortunately, almost all white dwarfs have hydrogen and/or helium envelopes that, while low in mass, are sufficiently thick to shield the core from direct view. However should such a core lose its remaining hydrogen envelope, astrophysicists could then detect an extremely oxygen-rich spectrum from the surface of the white dwarf.

LCROSS Impact Analysis Indicates Water On Moon

LCROSS Impact Analysis Indicates Water On Moon

ScienceDaily (Nov. 13, 2009) — The argument that the moon is a dry, desolate place no longer holds water.

Secrets the moon has been holding, for perhaps billions of years, are now being revealed to the delight of scientists and space enthusiasts alike.

NASA has opened a new chapter in our understanding of the moon. Preliminary data from the Lunar CRater Observation and Sensing Satellite, or LCROSS, indicates that the mission successfully uncovered water during the Oct. 9, 2009 impacts into the permanently shadowed region of Cabeus cater near the moon's south pole.

The impact created by the LCROSS Centaur upper stage rocket created a two-part plume of material from the bottom of the crater. The first part was a high angle plume of vapor and fine dust and the second a lower angle ejecta curtain of heavier material. This material has not seen sunlight in billions of years.

"We're unlocking the mysteries of our nearest neighbor and by extension the solar system. It turns out the moon harbors many secrets, and LCROSS has added a new layer to our understanding," said Michael Wargo, chief lunar scientist at NASA Headquarters in Washington.

Scientists have long speculated about the source of vast quantities of hydrogen that have been observed at the lunar poles. The LCROSS findings are shedding new light on the question of water, which could be more widespread and in greater quantity than previously suspected.